Mónica Sousa graduated in Biochemistry in 1994 from the University of Porto and on the same year she joined the Gulbenkian PhD Program in Biology and Medicine. She developed her PhD in the lab of Maria João Saraiva generating transgenic mouse models for the study of familial amyloid polyneuropathy. In 2000, Mónica joined as a postdoc fellow the lab of David Stern at Columbia University, New York to study neurodegeneration caused by the deposition of amyloid fibrils. Mónica was then hired by the IBMC- Porto in 2003 where she is currently the leader of the Nerve Regeneration group. The main interest of this group is to characterize pathways controlling axon growth and regeneration, with a particular emphasis in the analysis of cytoskeleton dynamics, and to use the acquired knowledge to design pre-clinical therapeutic approaches to promote axon regeneration. In this respect this group has been focusing in the model of spinal cord injury and in models of rare neurodegenerative disorders.